Prevalence of germline GATA2 and SAMD9/9L variants in paediatric haematological disorders with monosomy 7
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DOI: 10.1111/bjh.17006
Abstract: Monosomy 7 (−7) occurs in various types of paediatric myeloid disorders and has a poor prognosis. Recent studies have demonstrated that patients with germline gain‐of‐function SAMD9/9L variants and loss‐of‐function GATA2 variants are prone to developing… read more here.
Keywords: samd9 variants; gata2; gata2 samd9; germline ... See more keywords
Utility of the number needed to treat in paediatric haematological cancer randomised controlled treatment trials: a systematic review
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DOI: 10.1136/bmjopen-2018-022839
Abstract: Objectives The primary objective was to assess the utility of the number needed to treat (NNT) to inform decision-making in the context of paediatric oncology and to calculate the NNT in all superiority, parallel, paediatric… read more here.
Keywords: utility number; number needed; cancer; needed treat ... See more keywords