Paeoniflorin Ameliorates Chronic Stress-Induced Depression-Like Behaviors and Neuronal Damages in Rats via Activation of the ERK-CREB Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00772
Abstract: Neuronal damage is related to the onset and treatment of depressive disorders. Antidepressant-like effects have been elicited by paeoniflorin on animal models. The aim of this study is to demonstrate whether the neuroprotective effect of… read more here.
Keywords: paeoniflorin ameliorates; creb; stress; pathway ... See more keywords
Paeoniflorin ameliorates Aβ-stimulated neuroinflammation via regulation of NF-κB signaling pathway and Aβ degradation in C6 glial cells
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition Research and Practice"
DOI: 10.4162/nrp.2020.14.6.593
Abstract: BACKGROUND/OBJECTIVES Alzheimer's disease is common age-related neurodegenerative condition characterized by amyloid beta (Aβ) accumulation that leads cognitive impairment. In the present study, we investigated the protective effect of paeoniflorin (PF) against Aβ-induced neuroinflammation and the… read more here.
Keywords: paeoniflorin ameliorates; degradation; glial cells; neuroinflammation ... See more keywords