The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
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DOI: 10.7554/elife.79013
Abstract: UHRF1-dependent ubiquitin signaling plays an integral role in the regulation of maintenance DNA methylation. UHRF1 catalyzes transient dual mono-ubiquitylation of PAF15 (PAF15Ub2), which regulates the localization and activation of DNMT1 at DNA methylation sites during… read more here.
Keywords: paf15; dna methylation; ubiquitin signaling; termination ... See more keywords