Modulation of Tumor-Associated Macrophages (TAM) Phenotype by Platelet-Activating Factor (PAF) Receptor
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DOI: 10.1155/2017/5482768
Abstract: Platelet-activating factor (PAF) plays an important role in the pathogenesis of several types of tumors. The biological effects of PAF are mediated by the PAF receptor (PAFR), which can be expressed by tumor cells and… read more here.
Keywords: factor paf; platelet activating; activating factor; pafr ... See more keywords
PAFR selectively mediates radioresistance and irradiation-induced autophagy suppression in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14647
Abstract: Platelet-activating factor receptor (PAFR) promotes tumorigenesis, angiogenesis and metastasis. Here, we defined the PAFR as a yielding new inhibiting target to selectively enhance the sensitivity of prostate cancer (PCa) cells to radiation. The selective responding… read more here.
Keywords: autophagy suppression; prostate cancer; pafr;