Multicomponent Synthesis of Isoindolinones by RhIII Relay Catalysis: Synthesis of Pagoclone and Pazinaclone from Benzaldehyde.
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DOI: 10.1021/acs.orglett.8b04026
Abstract: A practical one-pot isoindolinone synthesis enabled by RhIII catalysis was developed. The advantage of this protocol is that it does not require pre-preparation of amide substrates, because RhIII participates in two reactions independently. This mild,… read more here.
Keywords: multicomponent synthesis; catalysis; pagoclone pazinaclone; synthesis isoindolinones ... See more keywords