Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c220004
Abstract: Serotonin is often referred to as a "happy hormone" as it maintains good mood, well-being, and happiness. It is involved in communication between nerve cells and plays a role in sleeping and digestion. However, too… read more here.
Keywords: serotonin; pulmonary hypertension; hypertension; serotonin synthesis ... See more keywords
Renal replacement therapy as a therapeutic option for right heart failure in severe pulmonary arterial hypertension.
Sign Up to like & getrecommendations! Published in 2022 at "ESC heart failure"
DOI: 10.1002/ehf2.13945
Abstract: Pulmonary arterial hypertension (PAH) is a progressively life-threatening disease that causes right heart failure (RHF). Renal dysfunction frequently complicates PAH with RHF and is associated with a worse prognosis. Renal replacement therapy (RRT) may be… read more here.
Keywords: pah; arterial hypertension; pulmonary arterial; heart failure ... See more keywords
Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3533
Abstract: Diluted bitumen (dilbit; the product of oil sands extraction) is transported through freshwater ecosystems critical to Pacific salmon. This is concerning, because crude oil disrupts cardiac development, morphology, and function in embryonic fish, and cardiac… read more here.
Keywords: dilbit; salmon; sockeye salmon; performance ... See more keywords
Later life swimming performance and persistent heart damage following subteratogenic PAH mixture exposure in the Atlantic killifish (Fundulus heteroclitus).
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3877
Abstract: High-level, acute exposures to individual polycyclic aromatic hydrocarbons (PAHs) and complex PAH mixtures result in cardiac abnormalities in developing fish embryos. Whereas acute PAH exposures can be developmentally lethal, little is known about the later… read more here.
Keywords: atlantic wood; king creek; swimming performance; performance ... See more keywords
Phenylalanine hydroxylase variants interact with the co‐chaperone DNAJC12
Sign Up to like & getrecommendations! Published in 2019 at "Human Mutation"
DOI: 10.1002/humu.23712
Abstract: DNAJC12, a type III member of the HSP40/DNAJ family, has been identified as the specific co‐chaperone of phenylalanine hydroxylase (PAH) and the other aromatic amino acid hydroxylases. DNAJ proteins work together with molecular chaperones of… read more here.
Keywords: pah; dnajc12; chaperone; phenylalanine hydroxylase ... See more keywords
Reducing polycyclic aromatic hydrocarbon contamination in smoked fish in the Global South: a case study of an improved kiln in Ghana.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9802
Abstract: BACKGROUND Smoked fish is a major source of animal protein in developing countries. It is largely produced by hot-smoking on traditional kilns using fuelwood. This practice is associated with high polycyclic aromatic hydrocarbon (PAH) contamination… read more here.
Keywords: aromatic hydrocarbon; polycyclic aromatic; improved kiln; contamination ... See more keywords
Hepatoma‐derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12007
Abstract: Abstract Hepatoma‐derived growth factor (HDGF) was previously shown to be associated with increased mortality in a small study of idiopathic and connective tissue disease‐associated pulmonary arterial hypertension (PAH). In this study, we measured serum HDGF… read more here.
Keywords: derived growth; disease; hepatoma derived; hdgf ... See more keywords
A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12051
Abstract: Abstract Pulmonary arterial hypertension (PAH) is a progressive, ultimately fatal cardiopulmonary disease associated with a number of physiologic changes, which is believed to result in imbalances in the intestinal microbiota. To date, comprehensive investigational analysis… read more here.
Keywords: arterial hypertension; microbiota; pulmonary arterial; pah ... See more keywords
Utilization of risk assessment tools in management of PAH: A PAH provider survey
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12057
Abstract: Abstract Pulmonary arterial hypertension (PAH) is a chronically progressive fatal disease. A goal‐oriented approach to achieve low risk status has been associated with improved survival. A variety of risk stratification tools are available, but use… read more here.
Keywords: risk tools; utilization; survey; risk ... See more keywords
Prospective clinical assessment of patients with pulmonary arterial hypertension switched from bosentan to macitentan (POTENT)
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12083
Abstract: Abstract Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH‐specific therapies allowed evolving from symptom‐based strategies to others aiming to move patients to low‐risk conditions. Endothelin‐1 (ET‐1) receptor antagonists emerged… read more here.
Keywords: arterial hypertension; macitentan; potent; pulmonary arterial ... See more keywords
INSPIRE: Safety and tolerability of inhaled Yutrepia (treprostinil) in pulmonary arterial hypertension (PAH)
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12119
Abstract: Abstract The INSPIRE trial was a Phase 3, open‐label, multicenter trial (LTI‐301) that enrolled patients with pulmonary arterial hypertension (PAH) ≥ 18 years of age who transitioned to Yutrepia from nebulized treprostinil (Transition) or added Yutrepia to… read more here.
Keywords: safety; hypertension pah; arterial hypertension; trial ... See more keywords