Relationships between sexual function, mental health, and quality of life of female patients with pulmonary arterial hypertension associated with congenital heart disease
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12164
Abstract: Abstract In recent years, the treatment of pulmonary arterial hypertension (PAH) has gradually increased, including new drugs and surgical methods, the mortality rate of PAH patients has significantly decreased, and the average survival rate has… read more here.
Keywords: pah patients; health; sexual function; mental health ... See more keywords
Metallomics in pulmonary arterial hypertension patients
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DOI: 10.1002/pul2.12202
Abstract: Abstract Pulmonary arterial hypertension (PAH) prevalence is increasing worldwide, and the prognosis is poor with 5‐year survival read more here.
Keywords: arterial hypertension; pah patients; pulmonary arterial; metal ... See more keywords
4973Efficacy and safety of selexipag in pulmonary arterial hypertension (PAH) patients with and without significant cardiovascular (CV) comorbidities
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0032
Abstract: Many PAH patients today have a number of CV comorbidities, yet data on the efficacy and safety of therapies in such patients remain scarce. Most recent PAH clinical trials also include patients with comorbidities. To… read more here.
Keywords: safety; patients comorbidities; pah patients; selexipag ... See more keywords
Abstract P143: Multifaceted Roles of Gut Microbiome and Bacterial Metabolites in Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p143
Abstract: Objectives: Pulmonary arterial hypertension (PAH) is a deadly disease without any effective cure. Identification of the PAH-associated gut microbiome may shift conceptual paradigms of the disease that could lead to new therapeutic advancement. We tested… read more here.
Keywords: pulmonary arterial; pah patients; arterial hypertension; gut microbiome ... See more keywords
Pulmonary Arterial Hypertension Patients Have a Proinflammatory Gut Microbiome and Altered Circulating Microbial Metabolites.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202203-0490oc
Abstract: RATIONALE Inflammation drives pulmonary arterial hypertension (PAH). Gut dysbiosis causes immune dysregulation and systemic inflammation by altering circulating microbial metabolites; however, little is known about gut dysbiosis and microbial metabolites in PAH. OBJECTIVES To characterize… read more here.
Keywords: microbial metabolites; circulating microbial; pah patients; pulmonary arterial ... See more keywords
Novel Loss of Function KCNA5 Variants in Pulmonary Arterial Hypertension.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0245oc
Abstract: Reduced expression and/or activity of Kv1.5 channels (encoded by KCNA5) is a common hallmark in human or experimental pulmonary arterial hypertension (PAH). Likewise, genetic variants in KCNA5 have been found in PAH patients, but their… read more here.
Keywords: function; arterial hypertension; kcna5 variants; pulmonary arterial ... See more keywords
A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology and Therapeutics"
DOI: 10.1177/10742484211069005
Abstract: Background: Little data is published describing the use of medications prescribed for pulmonary arterial hypertension (PAH) in patients receiving extracorporeal membrane oxygenation (ECMO). Even though many patients with PAH may require ECMO as a bridge… read more here.
Keywords: arterial hypertension; membrane oxygenation; pah patients; pulmonary arterial ... See more keywords
Letter to the Editor regarding “Could pulmonary arterial hypertension patients be at lower risk from severe COVID-19?”
Sign Up to like & getrecommendations! Published in 2020 at "Pulmonary Circulation"
DOI: 10.1177/2045894020925761
Abstract: It was with great interest and some concern we read the recently published paper ‘‘Could pulmonary arterial hypertension (PAH) patients be at lower risk from severe COVID19.’’ In this paper, the authors quote an electronic… read more here.
Keywords: patients lower; pah patients; hypertension; pah ... See more keywords
Volumetric capnography in PAH patients
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DOI: 10.1183/1393003.congress-2017.pa2401
Abstract: An increase of Pulmonary Arterial Systolic Pressure (PASP) during exercise in Pulmonary Arterial Hypertension(PAH) may indicate a good functional reserve of right ventricle. Volumetric Capnography(VCap) can reveal the ventilatory pattern of these patients. Objectives: to… read more here.
Keywords: volumetric capnography; reduced fvc; pah patients; capnography pah ... See more keywords
The Transition From Ambrisentan to Macitentan in Patients With Pulmonary Arterial Hypertension: A Real-word Prospective Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.811700
Abstract: Background: In a long-term event-driven trial, macitentan has demonstrated beneficial time to clinical worsening in patients with pulmonary arterial hypertension (PAH) and reduced PAH-related hospitalization rates compared with placebo. Macitentan is the most recently approved… read more here.
Keywords: macitentan; ambrisentan macitentan; pah patients; transition ... See more keywords
Egln1Tie2Cre Mice Exhibit Similar Therapeutic Responses to Sildenafil, Ambrisentan, and Treprostinil as Pulmonary Arterial Hypertension (PAH) Patients, Supporting Egln1Tie2Cre Mice as a Useful PAH Model
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032391
Abstract: Pulmonary arterial hypertension (PAH) is a progressive and inevitably fatal disease characterized by the progressive increase of pulmonary vascular resistance and obliterative pulmonary vascular remodeling, which lead to right-sided heart failure and premature death. Many… read more here.
Keywords: pah patients; pulmonary arterial; model; egln1tie2cre mice ... See more keywords