Articles with "pain model" as a keyword



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Amniotic Suspension Allograft Modulates Inflammation in a Rat Pain Model of Osteoarthritis

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Published in 2019 at "Journal of Orthopaedic Research"

DOI: 10.1002/jor.24559

Abstract: Osteoarthritis (OA) affects over 301 million adults worldwide. Inflammation is a recognized component of the OA process; two potent pro‐inflammatory cytokines involved in OA are interleukin‐1β and tumor necrosis factor‐α. Placental‐derived tissues and fluids are… read more here.

Keywords: amniotic suspension; suspension allograft; osteoarthritis; model ... See more keywords
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Pathway-Specific Alterations of Cortico-Amygdala Transmission in an Arthritis Pain Model.

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Published in 2018 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.8b00022

Abstract: Medial prefrontal cortex (mPFC) and amygdala are closely interconnected brain areas that play a key role in cognitive-affective aspects of pain through their reciprocal interactions. Clinical and preclinical evidence suggests that dysfunctions in the mPFC-amygdala… read more here.

Keywords: transmission; pathway; arthritis pain; pain model ... See more keywords
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Drosophila pain sensitization and modulation unveiled by a novel pain model and analgesic drugs

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Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0281874

Abstract: In mammals, pain is regulated by the combination of an ascending stimulating and descending inhibitory pain pathway. It remains an intriguing question whether such pain pathways are of ancient origin and conserved in invertebrates. Here… read more here.

Keywords: pain sensitization; pain model; sensitization modulation; pain ... See more keywords
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Antinociceptive Effect of a p-Cymene/β-cyclodextrin Inclusion Complex in a Murine Cancer Pain Model: Characterization Aided through a Docking Study

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28114465

Abstract: Pain is one of the most prevalent and difficult to manage symptoms in cancer patients, and conventional drugs present a range of adverse reactions. The development of β-cyclodextrins (β-CD) complexes has been used to avoid… read more here.

Keywords: cancer pain; effect; pain; pain model ... See more keywords