The antiviral alkaloid berberine ameliorates neuropathic pain in rats with peripheral nerve injury
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-018-1006-9
Abstract: Neuropathic pain is a major public health problem. There is a need to develop safer and more effective analgesia compounds with less side effects. Berberine has been used to treat diarrhea and gastroenteritis due to… read more here.
Keywords: pain rats; neuropathic pain; nerve injury; peripheral nerve ... See more keywords
Betaine Attenuates Chronic Constriction Injury-Induced Neuropathic Pain in Rats by Inhibiting KIF17-Mediated Nociception.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00380
Abstract: Kinesin superfamily proteins transport a diverse range of cargo, including excitatory receptors to the dendrite and axon of a neuron via retrograde and anterograde fashions along microtubules, causing central sensitization and neuropathic pain. In this… read more here.
Keywords: kif17; betaine; neuropathic pain; pain ... See more keywords
Antinociceptive Effects of Emodin on CFA-Induced Inflammatory Pain in Rats
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DOI: 10.1177/1934578x20942002
Abstract: The effect of emodin on complete Freund’s adjuvant (CFA)-induced inflammatory pain in rats and its potential molecular mechanism was investigated. For this, a rat model of inflammatory pain induced by CFA was established and rats… read more here.
Keywords: pain rats; inflammatory pain; cfa induced; pain ... See more keywords
Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats
Sign Up to like & getrecommendations! Published in 2022 at "Acta Pharmaceutica"
DOI: 10.2478/acph-2022-0037
Abstract: Abstract In the present study the interaction of cannabinoid, PhAR-DBH-Me [(R, Z)-18-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-18-oxooctadec-9-en-7-ylphenyl-acetate] and tramadol in two neuropathy models, as well as their possible toxic effects, was analyzed. The anti-allodynic effect of PhAR-DBH-Me, tramadol, or their… read more here.
Keywords: tramadol; neuropathic pain; pain rats; histology ... See more keywords