Brain imaging of pain sensitization in patients with knee osteoarthritis
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DOI: 10.1097/j.pain.0000000000000985
Abstract: Abstract A relevant aspect in osteoarthritic pain is neural sensitization. This phenomenon involves augmented responsiveness to painful stimulation and may entail a clinically worse prognosis. We used functional magnetic resonance imaging (fMRI) to study pain… read more here.
Keywords: sensitization patients; stimulation; knee osteoarthritis; pain sensitization ... See more keywords
Trauma and pain sensitization in youth with chronic pain
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DOI: 10.1097/pr9.0000000000000992
Abstract: Greater posttraumatic stress symptoms were associated with higher experimental pain tolerance. Pain may trigger dissociation in youth with chronic pain and higher posttraumatic stress symptoms. Abstract Introduction: Chronic pain (pain lasting ≥3 months) co-occurs with… read more here.
Keywords: pain sensitization; chronic pain; pain; youth chronic ... See more keywords
High Prevalence of Pain Sensitization in Knee Osteoarthritis: A Meta-Analysis with Meta-Regression
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DOI: 10.1177/19476035221087698
Abstract: Objective The aim of this meta-analysis was to study the evidence on pain sensitization in knee osteoarthritis (OA), providing a quantitative synthesis of its prevalence and impact. Factors associated with pain sensitization were also investigated.… read more here.
Keywords: pain sensitization; prevalence; meta analysis; pain ... See more keywords
Drosophila pain sensitization and modulation unveiled by a novel pain model and analgesic drugs
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DOI: 10.1371/journal.pone.0281874
Abstract: In mammals, pain is regulated by the combination of an ascending stimulating and descending inhibitory pain pathway. It remains an intriguing question whether such pain pathways are of ancient origin and conserved in invertebrates. Here… read more here.
Keywords: pain sensitization; pain model; sensitization modulation; pain ... See more keywords
Role of Etanercept and Infliximab on Nociceptive Changes Induced by the Experimental Model of Fibromyalgia
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DOI: 10.3390/ijms23116139
Abstract: Background: Fibromyalgia is a clinical condition that affects 1% to 5% of the population. No proper therapy has been currently found. It has been described that inflammation plays a central role in the nerve sensitizations… read more here.
Keywords: pain sensitization; infliximab nociceptive; role; etanercept infliximab ... See more keywords