Distribution of mast cell subtypes in interstitial cystitis: implications for novel diagnostic and therapeutic strategies?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2017-204881
Abstract: Aims To identify the presence and geographical distribution of mast cell (MC) subtypes: MCT (tryptase positive–chymase negative) and MCTC (tryptase positive–chymase positive) in bladder tissue. Methods Bladder tissue was obtained from patients with painful bladder… read more here.
Keywords: cystitis; interstitial cystitis; painful bladder; syndrome interstitial ... See more keywords
TRPV4 activation prevents lipopolysaccharide-induced painful bladder hypersensitivity in rats by regulating immune pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080302
Abstract: Chronic inflammation in the urinary bladder is a potential risk factor for bladder dysfunction, including interstitial cystitis/bladder pain syndrome (IC/BPS). Although several studies have reported that activation of transient receptor potential vanilloid 4 (TRPV4) contributes… read more here.
Keywords: trpv4 activation; painful bladder; bladder; bladder hypersensitivity ... See more keywords