Asymmetric base-pair opening drives helicase unwinding dynamics
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1901086116
Abstract: Significance Six decades after DNA structure was first revealed, fundamental questions remain open. How is the entwined embrace of double-stranded nucleic acids formed or disrupted? How does the energetics underlying this process influence nucleic-acid processing… read more here.
Keywords: double helix; pair opening; base pair; base ... See more keywords
Base-Pair Opening Dynamics Study of Fluoride Riboswitch in the Bacillus cereus CrcB Gene
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DOI: 10.3390/ijms22063234
Abstract: Riboswitches are segments of noncoding RNA that bind with metabolites, resulting in a change in gene expression. To understand the molecular mechanism of gene regulation in a fluoride riboswitch, a base-pair opening dynamics study was… read more here.
Keywords: opening dynamics; pair opening; fluoride riboswitch; base pair ... See more keywords