Shapeshifting tau: from intrinsically disordered to paired-helical filaments
Sign Up to like & getrecommendations! Published in 2022 at "Essays in Biochemistry"
DOI: 10.1042/ebc20220150
Abstract: Abstract Tau is an intrinsically disordered protein that has the ability to self-assemble to form paired helical and straight filaments in Alzheimer’s disease, as well as the ability to form additional distinct tau filaments in… read more here.
Keywords: ability; tau intrinsically; intrinsically disordered; paired helical ... See more keywords
Reflective-Type Multiparameter Sensor Based on a Paired Helical Fiber Gratings and a Trapezoid-Like Microcavity
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Instrumentation and Measurement"
DOI: 10.1109/tim.2022.3169556
Abstract: A reflective-type fiber sensor allowing the simultaneous measurements of directional torsion, strain, and temperature is proposed and experimentally demonstrated, which is realized by using a paired helical long-period fiber gratings and a trapezoid-like microcavity (PHLPGs-TLMC).… read more here.
Keywords: fiber gratings; reflective type; paired helical; fiber ... See more keywords
Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.988074
Abstract: Aggregation of the tau protein into fibrillar cross-β aggregates is a hallmark of Alzheimer’s diseases (AD) and many other neurodegenerative tauopathies. Recently, several core structures of patient-derived tau paired helical filaments (PHFs) have been solved… read more here.
Keywords: core; tau; paired helical; tau 297 ... See more keywords