Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch.
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DOI: 10.1021/acs.biochem.6b01175
Abstract: Spiroiminodihydantoin (Sp) is a hyperoxidized form of guanine (G) resulting from oxidation by reactive oxygen species. The lesion is highly mutagenic, and the stereocenter renders the two isomers with distinct behaviors in chemical, spectroscopic, enzymatic,… read more here.
Keywords: base pairing; hemolysin latch; base; base pairs ... See more keywords