EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental cell"
DOI: 10.1016/j.devcel.2019.05.043
Abstract: Macropinocytosis has emerged as an important nutrient-scavenging pathway that supports tumor cell fitness. By internalizing extracellular protein and targeting it for lysosomal degradation, this endocytic pathway functions as an amino acid supply route, permitting tumor… read more here.
Keywords: egfr pak; macropinocytosis; pak signaling; signaling selectively ... See more keywords
Multifaceted analysis of products from the intermediate co-pyrolysis of biomass with Tetra Pak waste
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hydrogen Energy"
DOI: 10.1016/j.ijhydene.2021.06.202
Abstract: Abstract This study investigates the co-pyrolysis of two types of biomass (pine bark and wheat straw) with Tetra Pak waste (TPW). The experiments were performed using a fixed-bed reactor equipped with an innovative system, where… read more here.
Keywords: multifaceted analysis; pak; tetra pak; pak waste ... See more keywords
Drug Induced Pneumonitis Secondary to Treatment with Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir (VIEKIRA PAK®) for Chronic Hepatitis C: Case Report of an Unexpected Life-Threatening Adverse Reaction
Sign Up to like & getrecommendations! Published in 2017 at "Case Reports in Medicine"
DOI: 10.1155/2017/4895736
Abstract: VIEKIRA PAK (ritonavir-boosted paritaprevir/ombitasvir and dasabuvir) is an approved treatment for compensated patients with genotype 1 (GT1) chronic hepatitis C virus (HCV) infection. This oral regimen has minimal adverse effects and is well tolerated. Cure… read more here.
Keywords: chronic hepatitis; treatment; viekira pak; pak ... See more keywords
Abstract B066: Unique roles of group I PAK isoforms in regulating MPNST cell viability
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-17-b066
Abstract: Group I p21-activated kinases (PAKs) include three members (PAK1, PAK2, and PAK3) that represent key components of several cell signaling networks. By transmitting growth factor-induced signals from Rho family GTPases, PAK1/2/3 regulate cytoskeletal dynamics, cell… read more here.
Keywords: pak isoforms; mpnst cell; group pak; group ... See more keywords
RhoJ facilitates angiogenesis in glioblastoma via JNK/VEGFR2 mediated activation of PAK and ERK signaling pathways
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.65653
Abstract: Glioblastoma (GBM) is a highly vascularized malignant tumor that depends on new blood vessel formation. Small molecules targeting the angiogenic process may be an effective anti-GBM therapeutic strategy. We previously demonstrated that RhoJ promoted the… read more here.
Keywords: rhoj; pak; jnk; erk ... See more keywords