EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis.
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DOI: 10.1016/j.devcel.2019.05.043
Abstract: Macropinocytosis has emerged as an important nutrient-scavenging pathway that supports tumor cell fitness. By internalizing extracellular protein and targeting it for lysosomal degradation, this endocytic pathway functions as an amino acid supply route, permitting tumor… read more here.
Keywords: egfr pak; macropinocytosis; pak signaling; signaling selectively ... See more keywords