PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3084
Abstract: Colorectal cancer (CRC) is the third‐most common cancer around the world, accounting for approximately 10% of cancer‐related mortality. Deeper molecular understanding of colorectal carcinogenesis will provide evidences for identification of early diagnostic indicators and novel… read more here.
Keywords: pak5; invasion; colorectal cancer; migration ... See more keywords
PAK5 is a potential target in myelodysplastic syndrome through interacting with LMO2 and GATA1.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.9.12
Abstract: Myelodysplastic syndrome (MDS) is a neoplastic heterogeneous and pre-leukemic disease with poor clinical outcome due to the failure of current chemotherapeutic strategies to target leukemic stem cells. Recently, we find that p21-activated kinase 5 (PAK5)… read more here.
Keywords: pak5 potential; lmo2 gata1; gata1; pak5 ... See more keywords
miR-489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Reports"
DOI: 10.3892/or.2019.7381
Abstract: Glioma patients receiving therapy are at a high risk of relapse and rapid progression and, thus, more effective treatments are required. The aim of the present study was to determine the suppressive role of miR-489… read more here.
Keywords: raf1; glioma; pak5; expression ... See more keywords