Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency.
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DOI: 10.1016/j.clim.2016.09.009
Abstract: Common variable immunodeficiency (CVID) is a heterogeneous group of primary immunodeficiency characterized by recurrent infections. We evaluated whether defective PI3K/Akt/FoxO pathway could influence B-cell fate. Determination of B-cell subsets in CVD patients and healthy donors… read more here.
Keywords: immunodeficiency; variable immunodeficiency; common variable; cells patients ... See more keywords