An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells.
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DOI: 10.1016/j.vascn.2018.02.005
Abstract: AKT is an enzyme of the PI3K/pAKT pathway, regulating proliferation and cell survival. High basal levels of active, phosphorylated AKT (pAKT) are associated with tumor progression and therapeutic resistance in some breast cancer subtypes, including… read more here.
Keywords: microscopy; pakt levels; automated epifluorescence; pakt ... See more keywords