SPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81123-9
Abstract: Cleft lip and/or palate (CL/P) are common anomalies occurring in 1/800 live-births. Pathogenic SPECC1L variants have been identified in patients with CL/P, which signifies a primary role for SPECC1L in craniofacial development. Specc1l mutant mouse… read more here.
Keywords: mepm; specc1l; palatal mesenchyme; mepm cells ... See more keywords
Generation of an immortalized mouse embryonic palatal mesenchyme cell line
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179078
Abstract: Palatogenesis is a complex morphogenetic process, disruptions in which result in highly prevalent birth defects in humans. In recent decades, the use of model systems such as genetically-modified mice, mouse palatal organ cultures and primary… read more here.
Keywords: embryonic palatal; generation immortalized; mouse embryonic; palatal mesenchyme ... See more keywords