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Safety and efficacy profile of cyclin‐dependent kinases 4/6 inhibitor palbociclib in cancer therapy: A meta‐analysis of clinical trials

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Published in 2019 at "Cancer Medicine"

DOI: 10.1002/cam4.1970

Abstract: Palbociclib is a small‐molecule, cyclin‐dependent kinase 4 and 6 inhibitor, which prevents phosphorylation of the retinoblastoma (Rb) protein and inhibits cell‐cycle progression from G1 to S phase. We performed this meta‐analysis to estimate the safety… read more here.

Keywords: cyclin dependent; safety efficacy; clinical trials; palbociclib cancer ... See more keywords