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Published in 2021 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2454
Abstract: This report examined the benefits and risks of palbociclib plus endocrine therapy (ET) in men with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC). Palbociclib was evaluated using 3 independent…
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Keywords:
real world;
treatment;
palbociclib plus;
world ... See more keywords
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Published in 2018 at "European journal of cancer"
DOI: 10.1016/j.ejca.2018.05.017
Abstract: AIM Because incidence of breast cancer and comorbidities increase with age, it is important to determine treatment benefit in elderly patients. We evaluated outcomes with palbociclib plus endocrine therapy in patients aged ≥65 years. METHODS…
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Keywords:
endocrine therapy;
palbociclib plus;
aged years;
breast cancer ... See more keywords
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Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz242.024
Abstract: Abstract Background Palbociclib, the first clinically available oral CDK4/6 inhibitor, in combination with endocrine therapy has become standard of care for HR+/HER2- advanced/metastatic breast cancer (MBC). No real-world studies have examined relative effectiveness of palbociclib…
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Keywords:
real world;
palbociclib;
pfizer inc;
palbociclib plus ... See more keywords
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1
Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.865292
Abstract: Background Cyclin-dependent kinase 4/6 inhibitors are a standard treatment for patients with hormone receptor−positive (HR+)/human epidermal growth factor receptor 2−negative (HER2−) metastatic breast cancer (MBC). However, real-world data on effectiveness in patients with liver or…
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Keywords:
metastasis;
palbociclib plus;
plus letrozole;
letrozole alone ... See more keywords
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Published in 2022 at "Current Oncology"
DOI: 10.3390/curroncol29020089
Abstract: This retrospective single-arm study assessed real-world treatment patterns and clinical outcomes in patients with hormone receptor—positive/human epidermal growth factor receptor 2—negative (HR+/HER2−) advanced/metastatic breast cancer (A/MBC) who received palbociclib plus an aromatase inhibitor as first-line…
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Keywords:
palbociclib plus;
world;
plus aromatase;
first line ... See more keywords