Articles with "palbociclib plus" as a keyword



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Real-World Data of Palbociclib in Combination With Endocrine Therapy for the Treatment of Metastatic Breast Cancer in Men.

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Published in 2021 at "Clinical pharmacology and therapeutics"

DOI: 10.1002/cpt.2454

Abstract: This report examined the benefits and risks of palbociclib plus endocrine therapy (ET) in men with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC). Palbociclib was evaluated using 3 independent… read more here.

Keywords: real world; treatment; palbociclib plus; world ... See more keywords
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Palbociclib plus endocrine therapy in older women with HR+/HER2- advanced breast cancer: a pooled analysis of randomised PALOMA clinical studies.

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Published in 2018 at "European journal of cancer"

DOI: 10.1016/j.ejca.2018.05.017

Abstract: AIM Because incidence of breast cancer and comorbidities increase with age, it is important to determine treatment benefit in elderly patients. We evaluated outcomes with palbociclib plus endocrine therapy in patients aged ≥65 years. METHODS… read more here.

Keywords: endocrine therapy; palbociclib plus; aged years; breast cancer ... See more keywords
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Comparative effectiveness of palbociclib plus letrozole vs letrozole for metastatic breast cancer in US real-world clinical practices

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Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz242.024

Abstract: Abstract Background Palbociclib, the first clinically available oral CDK4/6 inhibitor, in combination with endocrine therapy has become standard of care for HR+/HER2- advanced/metastatic breast cancer (MBC). No real-world studies have examined relative effectiveness of palbociclib… read more here.

Keywords: real world; palbociclib; pfizer inc; palbociclib plus ... See more keywords
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Real-World Effectiveness of Palbociclib Plus Letrozole vs Letrozole Alone for Metastatic Breast Cancer With Lung or Liver Metastases: Flatiron Database Analysis

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.865292

Abstract: Background Cyclin-dependent kinase 4/6 inhibitors are a standard treatment for patients with hormone receptor−positive (HR+)/human epidermal growth factor receptor 2−negative (HER2−) metastatic breast cancer (MBC). However, real-world data on effectiveness in patients with liver or… read more here.

Keywords: metastasis; palbociclib plus; plus letrozole; letrozole alone ... See more keywords
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Real-World Treatment Patterns and Clinical Effectiveness of Palbociclib Plus an Aromatase Inhibitor as First-Line Therapy in Advanced/Metastatic Breast Cancer: Analysis from the US Syapse Learning Health Network

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Published in 2022 at "Current Oncology"

DOI: 10.3390/curroncol29020089

Abstract: This retrospective single-arm study assessed real-world treatment patterns and clinical outcomes in patients with hormone receptor—positive/human epidermal growth factor receptor 2—negative (HR+/HER2−) advanced/metastatic breast cancer (A/MBC) who received palbociclib plus an aromatase inhibitor as first-line… read more here.

Keywords: palbociclib plus; world; plus aromatase; first line ... See more keywords