Palladium-catalysed aminocarbonylation/cyclization of iodoalkenes toward N-propargylcarboxamides and oxazoles
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2018.03.015
Abstract: Abstract Palladium(0) complexes formed in situ from a palladium(II) precursor, Pd(OAc)2, proved to be highly active catalytic system in aminocarbonylation of the variety of iodoalkenes (1-iodocyclohexene, 4-tert-butyl-1-iodocyclohexene, 2-methyl-1-iodocyclohexene, α-iodostyrene, 2-iodobornene, 17-iodoandrost-16-ene, 17-iodo-3-methoxyestra-1,3,5(10),16-tetraene, 20-iodo-3β-hydroxypregna-5,20-diene) using propargylamine… read more here.
Keywords: palladium; aminocarbonylation cyclization; palladium catalysed; catalysed aminocarbonylation ... See more keywords
Synthesis of benzamide-benzothiazole conjugates via palladium-catalysed aminocarbonylation (hydrazinocarbonylation)
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.02.026
Abstract: Abstract The palladium-catalysed aminocarbonylation of iodoarenes was investigated using 2-amino- and 2-hydrazinobenzothiazole as N-nucleophile. The reaction proved to be highly chemoselective in all cases: carboxamides and the corresponding carbohydrazides, obtained by the acylation at the… read more here.
Keywords: synthesis benzamide; catalysed aminocarbonylation; palladium catalysed;
Investigation of the palladium-catalysed cyclisation of α-amido malonates with propargylic compounds
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131866
Abstract: ABSTRACT Available online The palladium-catalysed cyclisation of propargylic electrophiles with nucleophiles represents a useful synthetic approach for the rapid construction of heterocyclic building blocks. However, these cyclisation reaction processes often pose a number of challenges… read more here.
Keywords: propargylic compounds; amido malonates; palladium catalysed; catalysed cyclisation ... See more keywords
Palladium-catalysed α-allylation of chiral sulfinimines derived from symmetric cyclic ketones
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.02.008
Abstract: Abstract A diastereoselective mono-allylation reaction at the α-position of symmetric cyclic ketones by using tert-butanesulfinamide as a chiral auxiliary is explored. Excellent yields and high diastereomeric ratios were achieved under palladium(0) catalysis in the presence… read more here.
Keywords: symmetric cyclic; catalysed allylation; allylation chiral; cyclic ketones ... See more keywords
Palladium-catalysed cross-coupling of lithium acetylides
Sign Up to like & getrecommendations! Published in 2020 at "Nature Catalysis"
DOI: 10.1038/s41929-020-0485-2
Abstract: The incorporation of alkynes into organic molecules is one of the most valuable transformations for the formation of C–C bonds and provides a versatile handle for further modifications. The Sonogashira cross-coupling of acetylenes holds a… read more here.
Keywords: lithium acetylides; cross; palladium catalysed; coupling lithium ... See more keywords
Palladium-catalysed intramolecular carbenoid insertion of α-diazo-α-(methoxycarbonyl)acetanilides for oxindole synthesis.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc00718c
Abstract: A novel, selective palladium-catalysed carbenoid C(aryl)-H insertion of α-diazo-α-(methoxycarbonyl)acetanilides leading to oxindoles is described. read more here.
Keywords: insertion diazo; diazo methoxycarbonyl; palladium catalysed; methoxycarbonyl acetanilides ... See more keywords
Mild palladium-catalysed highly efficient hydrogenation of CN, C–NO2, and CO bonds using H2 of 1 atm in H2O
Sign Up to like & getrecommendations! Published in 2019 at "Green Chemistry"
DOI: 10.1039/c8gc03285h
Abstract: Here we present the first example of a mild and high-efficiency protocol enabling a process in water using 1 atm of H2 for the efficient and selective hydrogenation of nitriles, nitro compounds, ketones, and aldehydes… read more here.
Keywords: using atm; palladium catalysed; mild palladium; highly efficient ... See more keywords
Palladium-catalysed dearomative aryl/cycloimidoylation of indoles.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc00402b
Abstract: The first example of a dearomative palladium-catalysed isocyanide insertion reaction has been developed using functionalized isocyanides as the reaction partner of N-(2-bromobenzoyl)indoles. The imidoyl-palladium intermediate generated by tandem indole double bond/isocyanide insertion reactions could be… read more here.
Keywords: aryl cycloimidoylation; cycloimidoylation indoles; dearomative aryl; palladium catalysed ... See more keywords
Alkali halides as nucleophilic reagent sources for N-directed palladium-catalysed ortho-C–H halogenation of s-tetrazines and other heteroaromatics
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra06169d
Abstract: A general palladium-catalysed selective C–H halogenation reaction is reported, which was successfully achieved for a large variety of functionalized aromatic rings incorporating diverse N-directing groups. By using simple alkali halides of MX type as the… read more here.
Keywords: nucleophilic reagent; alkali halides; halogenation; palladium catalysed ... See more keywords
Palladium-catalysed C–H arylation of benzophospholes with aryl halides
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04311d
Abstract: A palladium-catalysed C–H arylation of benzophospholes with aryl halides has been developed. The reaction with aryl iodides and bromides proceeds well even under phosphine ligand-free Pd(OAc)2 catalysis whereas the Pd(PCy3)2 is effective for the coupling… read more here.
Keywords: palladium catalysed; benzophospholes aryl; aryl halides; catalysed arylation ... See more keywords
Palladium-catalysed enantio- and regioselective (3 + 2) cycloaddition reactions of sulfamidate imine-derived 1-azadienes towards spirocyclic cyclopentanes
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d3sc01510f
Abstract: An enantio- and diastereoselective Pd-catalysed (3 + 2) cycloaddition of bis(trifluoroethyl) 2-vinyl-cyclopropane-1,1-dicarboxylate (VCP) with cyclic sulfamidate imine-derived 1-azadienes (SDAs) has been developed. These reactions provide highly functionalized spiroheterocycles having three contiguous stereocentres, including a tetrasubstituted… read more here.
Keywords: derived azadienes; palladium catalysed; imine; imine derived ... See more keywords