α ‐C−H Arylation of N ‐Sulfonyl Amines by Dual Palladium Catalysis
Sign Up to like & getrecommendations! Published in 2023 at "ChemCatChem"
DOI: 10.1002/cctc.202300392
Abstract: Functionalization of C(sp3)−H bonds adjacent to a nitrogen atom is an efficient means of preparing structurally complex amines and has long been of interest to synthetic chemists. Herein, dual palladium catalysis is used to achieve… read more here.
Keywords: arylation; dual palladium; palladium; palladium catalysis ... See more keywords
Unactivated Alkyl Chloride Reactivity in Excited-State Palladium Catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c02467
Abstract: Excited-state palladium catalysis is an efficient process for the alkylation of diverse organic compounds via the generation of alkyl radicals from alkyl bromides and iodides. However, the generation of alkyl radicals from more stable alkyl… read more here.
Keywords: state palladium; excited state; palladium catalysis;
Photoinduced Desaturation of Amides by Palladium Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02594
Abstract: A photoinduced palladium-catalyzed desaturation method that is suitable for converting the linear amides to their α,β-unsaturated counterparts is reported. The reaction does not require strong base/acid or sulfur/selenium and oxidant reagents and can be carried… read more here.
Keywords: amides palladium; desaturation amides; photoinduced desaturation; palladium catalysis ... See more keywords
Asymmetric Assemblies of 1,3-Dienes, Sulfuric Diamide, and Aldehydes to Access 1,3-Diamines through Relay Amine/Palladium Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03762
Abstract: A relay catalytic protocol using pyrrolidine and palladium catalysis has been developed for asymmetric synthesis of 1,3-diamine derivatives from 3-substituted 1,3-dienes, sulfuric diamide, and aldehydes. This one-pot, three-component reaction features the advantages of a high… read more here.
Keywords: dienes sulfuric; palladium catalysis; diamide aldehydes; sulfuric diamide ... See more keywords
Highly Diastereoselective Synthesis of Trifluoromethyl Indolines by Interceptive Benzylic Decarboxylative Cycloaddition of Nonvinyl, Trifluoromethyl Benzoxazinanones with Sulfur Ylides under Palladium Catalysis.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00237
Abstract: A highly diastereoselective synthesis of trifluoromethyl-substituted indolines under palladium catalysis is disclosed. The reaction proceeds by interceptive decarboxylative benzylic cycloaddition (IDBC) of nonvinyl, trifluoromethyl benzoxazinanones with sulfur ylides. The palladium-π-benzyl zwitterionic intermediates are suggested for… read more here.
Keywords: nonvinyl trifluoromethyl; diastereoselective synthesis; palladium catalysis; synthesis trifluoromethyl ... See more keywords
Asymmetric Organocatalysis Combined with Palladium Catalysis: Synergistic Effect on Enantioselective Mannich/α-Allylation Sequential Reactions of Pyrazolones in Constructing Vicinal Quaternary Stereocenters.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02440
Abstract: In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines… read more here.
Keywords: methodology; organocatalysis combined; asymmetric organocatalysis; palladium catalysis ... See more keywords
Enantioselective Double Carbonylation Enabled by High-Valent Palladium Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10559
Abstract: Palladium-catalyzed carbonylation reactions are efficient methods for synthesizing valuable molecules. However, realizing a carbonylation with excellent yield and chemo-, regio-, and enantioselectivities by classical low-valent palladium catalysis is highly challenging. Herein, we describe an enantioselective… read more here.
Keywords: palladium catalysis; valent palladium; carbonylation; palladium ... See more keywords
Reversible C–C bond formation using palladium catalysis
Sign Up to like & getrecommendations! Published in 2022 at "Nature Chemistry"
DOI: 10.1038/s41557-022-00898-0
Abstract: A widely appreciated principle is that all reactions are fundamentally reversible. Observing reversible transition metal-catalysed reactions, particularly those that include the cleavage of C–C bonds, is more challenging. The development of palladium- and nickel-catalysed carboiodination… read more here.
Keywords: formation using; bond formation; bond; reversible bond ... See more keywords
Ligand-controlled regiodivergent π-allyl palladium catalysis enables a switch between [3+2] and [3+3] cycloadditions.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc00611g
Abstract: Reported herein is the use of ligands to tune the regioselectivity and reactivity of palladium-catalyzed [3+2] and [3+3] cycloadditions. Diverse synthesis with vinylethylene carbonates (VECs) as well as free naphthols has been explored to construct… read more here.
Keywords: regiodivergent allyl; controlled regiodivergent; palladium catalysis; ligand controlled ... See more keywords