Construction of Axially Chiral Biaryl Sulfonamides by Palladium/Chiral Norbornene Cooperative Catalysis
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DOI: 10.1002/cctc.202500560
Abstract: Aryl sulfonamide scaffold is a privileged pharmacophore, and is prevalent in pharmaceuticals. Existing aryl sulfonamide‐based pharmaceuticals are either achiral or limited to central chirality, leaving the potential of axially chiral biaryl sulfonamides underexplored. Beyond therapeutic… read more here.
Keywords: axially chiral; palladium chiral; chiral norbornene; biaryl sulfonamides ... See more keywords