Regioselective C-H Active Carbonylation via 1,4-Palladium Migration.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00567
Abstract: We report a highly regioselective three-component coupling reaction of styrene, CO gas, and an amine compound to synthesize multisubstituted α,β-unsaturated amides, which involves a palladium-catalyzed sequential 1,4-palladium migration, C(sp2)-H activation, carbonylation, and amination. Salient features… read more here.
Keywords: regioselective active; palladium migration; palladium; active carbonylation ... See more keywords
Intramolecular Remote C-H Activation via Sequential 1,4-Palladium Migration To Access Fused Polycycles.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02392
Abstract: An unprecedented intramolecular remote C-H activation via sequential 1,4-palladium migration with an aromatic ring as a conveyor has been described. This reaction provides an efficient route to construct diverse polycyclic frameworks in moderate to good… read more here.
Keywords: palladium migration; intramolecular remote; remote activation;
Highly Regioselective C–H Alkylation of Alkenes Through an Aryl to Vinyl 1,4-Palladium Migration/C–C Cleavage Cascade
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04161
Abstract: Palladium-catalyzed C−H alkylation of gem-disubstituted ethylenes has been efficiently achieved with cyclobutanols as the coupling partners through an aryl to vinyl 1,4-palladium migration/ring-opening C–C cleavage cascade, giving trisubstituted alkenes in high yields. The protocol features… read more here.
Keywords: cleavage; palladium migration; aryl vinyl; palladium ... See more keywords