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   Articles with "pallidum subsp" as a keyword



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Estimation of Full-Length TprK Diversity in Treponema pallidum subsp. pallidum

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recommendations! Published in 2020 at "mBio"

DOI: 10.1128/mbio.02726-20

Abstract: Syphilis continues to be a significant public health issue in both low- and high-income countries, including the United States where the rate of syphilis infection has increased over the past 5 years. Treponema pallidum subsp.… read more here.

Keywords: pallidum subsp; pallidum; full length; subsp pallidum ... See more keywords
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Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart

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recommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0005894

Abstract: Background Treponema pallidum subsp. pertenue (TPE) is the causative agent of yaws, a multi-stage disease, endemic in tropical regions of Africa, Asia, Oceania, and South America. To date, four TPE strains have been completely sequenced… read more here.

Keywords: ghana; tpe; genome sequences; rate ... See more keywords

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

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recommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0007076

Abstract: Background Gallium is a semi-metallic element known since the 1930s to have antimicrobial activity. This activity stems primarily from gallium's ability to mimic trivalent iron and disrupt specific Fe(III)-dependent pathways, particularly DNA synthesis (due to… read more here.

Keywords: treponema pallidum; subsp pertenue; gallium maltolate; gallium ... See more keywords
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Clonal isolates of Treponema pallidum subsp. pallidum Nichols provide evidence for the occurrence of microevolution during experimental rabbit infection and in vitro culture

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recommendations! Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0281187

Abstract: The recent development of a system for long-term in vitro culture of the syphilis spirochete, Treponema pallidum subsp. pallidum, has introduced the possibility of detailed genetic analysis of this bacterium. In this study, the in… read more here.

Keywords: pallidum; vitro culture; subsp pallidum; pallidum subsp ... See more keywords
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Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis

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recommendations! Published in 2023 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1011259

Abstract: Background The TprK protein of the syphilis agent, Treponema pallidum subsp. pallidum (T. pallidum), undergoes antigenic variation in seven discrete variable (V) regions via non-reciprocal segmental gene conversion. These recombination events transfer information from a… read more here.

Keywords: pallidum; variation; pallidum subsp; strain ... See more keywords
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Multilocus sequence typing of Treponema pallidum subsp. pallidum in Barcelona.

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recommendations! Published in 2021 at "Future microbiology"

DOI: 10.2217/fmb-2021-0037

Abstract: Aim: To implement the multilocus sequence typing (MLST) methodology in syphilis samples previously characterized by enhanced CDC typing (ECDCT) and macrolide resistance. Materials & methods: MLST was performed on genital ulcer and blood samples by… read more here.

Keywords: subsp pallidum; pallidum subsp; pallidum; sequence typing ... See more keywords

A public database for the new MLST scheme for Treponema pallidum subsp. pallidum: surveillance and epidemiology of the causative agent of syphilis

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recommendations! Published in 2019 at "PeerJ"

DOI: 10.7717/peerj.6182

Abstract: Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted disease with worldwide prevalence. Several different molecular typing schemes are currently available for this pathogen. To enable population biology studies of the… read more here.

Keywords: treponema pallidum; subsp pallidum; causative agent; epidemiology ... See more keywords