5-Bromoprotocatechualdehyde Combats against Palmitate Toxicity by Inhibiting Parkin Degradation and Reducing ROS-Induced Mitochondrial Damage in Pancreatic β-Cells
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DOI: 10.3390/antiox10020264
Abstract: Pancreatic β-cell loss is critical in diabetes pathogenesis. Up to now, no effective treatment has become available for β-cell loss. A polyphenol recently isolated from Polysiphonia japonica, 5-Bromoprotocatechualdehyde (BPCA), is considered as a potential compound… read more here.
Keywords: combats palmitate; palmitate toxicity; bromoprotocatechualdehyde combats; toxicity inhibiting ... See more keywords
Effect of cis- and trans-Monounsaturated Fatty Acids on Palmitate Toxicity and on Palmitate-induced Accumulation of Ceramides and Diglycerides
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DOI: 10.3390/ijms21072626
Abstract: Dietary trans fatty acids (TFAs) have been implicated in serious health risks, yet little is known about their cellular effects and metabolism. We aim to undertake an in vitro comparison of two representative TFAs (elaidate… read more here.
Keywords: cis; accumulation; palmitate toxicity; palmitate ... See more keywords