Capmatinib improves insulin sensitivity and inflammation in palmitate-treated C2C12 myocytes through the PPARĪ“/p38-dependent pathway
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2021.111364
Abstract: Capmatinib (CAP) has been used to treat metastatic non-small lung cancer (NSCL) and suppress inflammation. It causes hypoglycemia in NSCL patients. Therefore, it is expected that CAP improves inflammation-mediated insulin resistance due to its anti-inflammatory… read more here.
Keywords: palmitate treated; palmitate; treated c2c12; inflammation ... See more keywords
Palmitate treated-astrocyte conditioned medium contains increased glutathione and interferes in hypothalamic synaptic network in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2018.08.010
Abstract: &NA; Excessive fat consumption increases the level of fatty acids (FAs) in the blood, which reach the hypothalamus and damage the circuit related to energy balance. In the present study, we used palmitate in a… read more here.
Keywords: treated astrocyte; palmitate; palmitate treated; medium ... See more keywords