Natural Ceramides and Lysophospholipids Cosegregate in Fluid Phosphatidylcholine Bilayers.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.02.002
Abstract: The mode of interactions between palmitoyl lysophosphatidylcholine (palmitoyl lyso-PC) or other lysophospholipids (lyso-PLs) and palmitoyl ceramide (PCer) or other ceramide analogs in dioleoylphosphatidylcholine (DOPC) bilayers has been examined. PCer is known to segregate laterally into… read more here.
Keywords: pcer; lyso pls; ceramide; palmitoyl ... See more keywords
Synthesis and Characterization of Palmitoyl-block-poly(methacryloyloxyethyl Phosphorylcholine) Polymer Micelles for Anticancer Drug Delivery.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00838
Abstract: We report the synthesis and characterization of an amphiphilic polymer comprising a hydrophobic palmitoyl group and a zwitterionic poly(2-methacryloyloxyethyl phosphorylcholine) (pMPC) block, which is capable of forming micelles as a drug carrier system for delivering… read more here.
Keywords: block; polymer; palmitoyl; drug ... See more keywords
Amphiphilic Chitosan Bearing Double Palmitoyl Chains and Quaternary Ammonium Moieties as a Nanocarrier for Plasmid DNA
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DOI: 10.1021/acsomega.1c06101
Abstract: Amphiphilic chitosan, bPalm-CS-HTAP, having N-(2-((2,3-bis(palmitoyloxy)propyl)amino)-2-oxoethyl) (bPalm) groups as double hydrophobic tails and O-[(2-hydroxyl-3-trimethylammonium)] propyl (HTAP) groups as hydrophilic heads was synthesized and evaluated for its self-assembly properties and potential as a gene carrier. The degree… read more here.
Keywords: bearing double; amphiphilic chitosan; htap; chitosan bearing ... See more keywords
Total Chemical Synthesis of Palmitoyl-Conjugated Insulin
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DOI: 10.1021/acsomega.2c07918
Abstract: Commercially available insulins are manufactured by recombinant methods for the treatment of diabetes. Long-acting insulin drugs (e.g., detemir and degludec) are obtained by fatty acid conjugation at LysB29 ε-amine of insulin via acid–amide coupling. There… read more here.
Keywords: insulin; synthesis palmitoyl; palmitoyl; chemical synthesis ... See more keywords