The NMDA receptor intracellular C‐terminal domains reciprocally interact with allosteric modulators
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.11.018
Abstract: &NA; N‐methyl‐D‐aspartate receptors (NMDARs) have multiple prominent roles in CNS function but their excessive or insufficient activity contributes to neuropathological/psychiatric disorders. Consequently, a variety of positive and negative allosteric modulators (PAMs and NAMs, respectively) have… read more here.
Keywords: terminal domains; allosteric modulators; intracellular terminal; pam activity ... See more keywords