PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio
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DOI: 10.1038/s41598-020-63143-z
Abstract: Inflammation of the gastrointestinal tract contributes to the development of inflammatory bowel disease (IBD). Human IBD is modeled by administering dextran sulfate sodium (DSS) to mice. In humans and mice, inflammatory M1 macrophages contribute to… read more here.
Keywords: pam3 protects; protects dss; dss induced; colitis ... See more keywords
Differential Effects of TLR1/2 and TLR2/6 Signaling on Normal and Premalignant Hematopoietic Stem and Progenitor Cells
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DOI: 10.1182/blood-2018-99-119719
Abstract: Prior studies from our lab and others have demonstrated a role for Toll-like receptor 2 (TLR2) in regulating both normal and premalignant hematopoietic stem and progenitor cells (HSPCs), however the contributions of its binding partners,… read more here.
Keywords: pam3; treated pam2; mice treated; mice ... See more keywords