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   Articles with "pam3csk4" as a keyword



Roles of serum in innate immune responses of human leukocytes to synthetic lipopeptide

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recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.06.006

Abstract: Abstract Tripalmitoyl‐S‐glyceryl‐l‐Cys‐Ser‐(Lys)4 (Pam3CSK4) is a highly conserved molecular motif found in various classes of lipoproteins. The requirement for leukocyte to respond to synthetic Pam3CSK4 were studied. Pam3CSK4 primed neutrophils for a respiratory burst in a… read more here.

Keywords: respiratory burst; pam3csk4; serum dependent; pam3csk4 induced ... See more keywords

RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern.

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recommendations! Published in 2022 at "Chemical communications"

DOI: 10.1039/d1cc06520c

Abstract: The coronavirus 2019 (COVID-19) pandemic is causing serious impacts in the world, and safe and effective vaccines and medicines are the best methods to combat the disease. The receptor-binding domain (RBD) of the SARS-CoV-2 spike… read more here.

Keywords: rbd; pam3csk4; variants concern; tlr1 agonist ... See more keywords

Delineating Brainstem CircRNAs role in Neonatal sepsis

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recommendations! Published in 2024 at "Physiology"

DOI: 10.1152/physiol.2024.39.s1.2141

Abstract: Background: Neonatal sepsis remains one of the leading causes of mortality in newborns. Despite advances in newborn care, the literature still deprived of mechanistic insights into neonatal sepsis. Our prior findings revealed that systemic inflammation… read more here.

Keywords: physiology; neonatal sepsis; pam3csk4; brainstem circrnas ... See more keywords

Pam3CSK4 Induces MMP-9 Expression in Human Monocytic THP-1 Cells

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recommendations! Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000475298

Abstract: Background: Matrix metalloproteinase (MMP)-9 is known to degrade the extracellular matrix and increased MMP-9 levels are related with the pathogenesis of many inflammatory conditions including obesity. Pam3CSK4 is a synthetic triacylated lipopeptide (LP) which is… read more here.

Keywords: pam3csk4; mmp expression; thp; thp cells ... See more keywords