Roles of serum in innate immune responses of human leukocytes to synthetic lipopeptide
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.06.006
Abstract: Abstract Tripalmitoyl‐S‐glyceryl‐l‐Cys‐Ser‐(Lys)4 (Pam3CSK4) is a highly conserved molecular motif found in various classes of lipoproteins. The requirement for leukocyte to respond to synthetic Pam3CSK4 were studied. Pam3CSK4 primed neutrophils for a respiratory burst in a… read more here.
Keywords: respiratory burst; pam3csk4; serum dependent; pam3csk4 induced ... See more keywords
RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06520c
Abstract: The coronavirus 2019 (COVID-19) pandemic is causing serious impacts in the world, and safe and effective vaccines and medicines are the best methods to combat the disease. The receptor-binding domain (RBD) of the SARS-CoV-2 spike… read more here.
Keywords: rbd; pam3csk4; variants concern; tlr1 agonist ... See more keywords
Pam3CSK4 Induces MMP-9 Expression in Human Monocytic THP-1 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000475298
Abstract: Background: Matrix metalloproteinase (MMP)-9 is known to degrade the extracellular matrix and increased MMP-9 levels are related with the pathogenesis of many inflammatory conditions including obesity. Pam3CSK4 is a synthetic triacylated lipopeptide (LP) which is… read more here.
Keywords: pam3csk4; mmp expression; thp; thp cells ... See more keywords