Nano-carrier Polyamidoamine Dendrimer G4 Induces Mitochondrial-dependent Apoptosis in Human Multidrug-resistant Breast Cancer Cells through G0/G1 Phase Arrest.
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DOI: 10.2174/1389201023666220822150050
Abstract: BACKGROUND Multidrug-resistant tumor cells have special drug detoxification/inactivation mechanisms. The terminal amino groups of the polyamidoamine (PAMAM-NH2), which is cytotoxic to tumor sensitive cells, may have no cytotoxicity in tumor resistant cells with mechanism different… read more here.
Keywords: adr cells; pamam nh2; multidrug resistant; mcf adr ... See more keywords