Insoluble Salt of Memantine with a Unique Fluorescence Phenomenon.
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DOI: 10.1021/acs.molpharmaceut.1c00931
Abstract: Alzheimer's disease is a chronic disease, and the long-term treatment of chronic diseases has always been a concern. Memantine (Mem) is approved by the US Food and Drug Administration for the treatment of moderate to… read more here.
Keywords: pamoic acid; unique fluorescence; fluorescence; memantine ... See more keywords
Selecting Counterions to Improve Ionized Hydrophilic Drug Encapsulation in Polymeric Nanoparticles.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00855
Abstract: Hydrophobic ion pairing (HIP) can successfully increase the drug loading and control the release kinetics of ionizable hydrophilic drugs, addressing challenges that prevent these molecules from reaching the clinic. Nevertheless, polymeric nanoparticle (PNP) formulation development… read more here.
Keywords: pamoic acid; counterions improve; hydrophilic drug; drug ... See more keywords