31P and 1H NMR Studies of the Molecular Organization of Lipids in the Parallel Artificial Membrane Permeability Assay.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.6b00889
Abstract: The parallel artificial membrane permeability assay (PAMPA) has emerged as a widely used primary in vitro screen for passive permeability of potential drug candidates. However, the molecular structure of the permeation barrier (consisting of a… read more here.
Keywords: membrane permeability; pampa; artificial membrane; permeability ... See more keywords
Efficacy of guselkumab, a selective IL-23 inhibitor, in Preventing Arthritis in a Multicentre Psoriasis At-Risk cohort (PAMPA): protocol of a randomised, double-blind, placebo controlled multicentre trial
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-063650
Abstract: Introduction Psoriatic arthritis (PsA) is a complex, immune-mediated disease associated with skin psoriasis that, if left untreated, can lead to joint destruction. Up to 30% of patients with psoriasis progress to PsA. In most cases,… read more here.
Keywords: arthritis; double blind; risk; pampa ... See more keywords
Communities of predatory mites (Phytoseiidae and Stigmaeidae) in different environments of the Brazilian Pampa
Sign Up to like & getrecommendations! Published in 2021 at "Acarologia"
DOI: 10.24349/acarologia/20214413
Abstract: The Brazilian Pampa presents a high diversity of fauna and flora within a mosaic of environments. The aim of this study was to evaluate the assemblages of predatory mites (Phytoseiidae and Stigmaeidae) in three different… read more here.
Keywords: phytoseiidae stigmaeidae; predatory mites; brazilian pampa; mites phytoseiidae ... See more keywords
Optimization of experimental conditions for skin-PAMPA measurements
Sign Up to like & getrecommendations! Published in 2020 at "ADMET and DMPK"
DOI: 10.5599/admet.761
Abstract: In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA. In the present work, the… read more here.
Keywords: pampa; skin pampa; optimization experimental; permeability ... See more keywords