A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.08.073
Abstract: SUMMARY Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to inhibit differentiation,… read more here.
Keywords: ocular neovascularization; pan antagonist; small molecule; molecule pan ... See more keywords