Articles with "pan class" as a keyword



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Abstract LB252: Evaluation of the pan-class I phosphoinositide 3-kinase (PI3K) inhibitor copanlisib in the Pediatric Preclinical Testing Consortium osteosarcomain vivomodels

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Published in 2021 at "Tumor Biology"

DOI: 10.1158/1538-7445.am2021-lb252

Abstract: Background. Copanlisib is a pan-class I phosphoinositide 3-kinase (PI3K) inhibitor with activity against all four PI3K class I isoforms (PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ). Copanlisib was approved for use by the FDA in the treatment… read more here.

Keywords: copanlisib; phosphoinositide kinase; pan class; pi3k ... See more keywords