A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments
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DOI: 10.1038/s41467-022-28045-w
Abstract: A genetic knockout can be lethal to one human cell type while increasing growth rate in another. This context specificity confounds genetic analysis and prevents reproducible genome engineering. Genome-wide CRISPR compendia across most common human… read more here.
Keywords: pan crispr; analysis; genome scale; cell ... See more keywords