Avasimibe: A novel hepatitis C virus inhibitor that targets the assembly of infectious viral particles
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.10.016
Abstract: ABSTRACT Directâacting antivirals (DAAs), which target hepatitis C virus (HCV) proteins, have exhibited impressive efficacy in the management of chronic hepatitis C. However, the concerns regarding high costs, drug resistance mutations and subsequent unexpected side… read more here.
Keywords: inhibitor; pan genotypic; hcv; hepatitis virus ... See more keywords
Strategy and Efficacy of Generic and Pan-genotypic Sofosbuvir/Velpatasvir in Chronic Hepatitis C Virus: A Myanmar Experience.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical and experimental hepatology"
DOI: 10.1016/j.jceh.2018.12.001
Abstract: Background In resource-constrained areas, generic direct-acting antivirals (DAAs) have considerably reduced the cost of hepatitis C virus (HCV) therapy while there remain significant costs related to the baseline and follow-up virologic assays. Aim The aim… read more here.
Keywords: genotype; treatment; pan genotypic; sof vel ... See more keywords
A bivalent HCV peptide vaccine elicits pan-genotypic neutralizing antibodies in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.08.066
Abstract: Vaccine development for antigenically variable pathogens has faltered because extreme genetic diversity precludes induction of broadly neutralizing antibodies (nAB) with classical vaccines. Here, using the most variable epitope of any known human pathogen (HVR1 of… read more here.
Keywords: neutralizing antibodies; bivalent hcv; pan genotypic; vaccine ... See more keywords
Development and Validation of a Pan-Genotypic Real-Time Quantitative Reverse Transcription-PCR Assay To Detect Canine Distemper Virus and Phocine Distemper Virus in Domestic Animals and Wildlife
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02505-21
Abstract: Canine distemper virus (CDV) is an animal morbillivirus belonging to the family Paramyxoviridae and has caused major epizootics with high mortality levels in susceptible wildlife species. In recent years, the documented genetic diversity of CDV… read more here.
Keywords: distemper virus; canine distemper; virus; pan genotypic ... See more keywords
Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-058757
Abstract: Introduction Low-cost generic direct-acting antiviral (DAA) regimens for treatment of hepatitis C virus (HCV) are available in several low-income/middle-income countries, important for treatment scale-up. This study evaluated the cost-effectiveness of genotype-dependent and pan-genotypic DAA regimens… read more here.
Keywords: pan genotypic; cost; scenario; treatment ... See more keywords