'Piperazining' the catalytic gatekeepers: unraveling the pan-inhibition of SRC kinases; LYN, FYN and BLK by masitinib.
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DOI: 10.4155/fmc-2018-0354
Abstract: Aim: Blocking oncogenic signaling of B-cell receptor (BCR) has been explored as a viable strategy in the treatment of diffuse large B-cell lymphoma. Masitinib is shown to multitarget LYN, FYN and BLK kinases that propagate… read more here.
Keywords: fyn; blk; lyn fyn; fyn blk ... See more keywords