Combination treatment of cancer cells with pan-Akt and pan-mTOR inhibitors: effects on cell cycle distribution, p-Akt expression level and radiolabelled-choline incorporation
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DOI: 10.1007/s10637-018-0642-5
Abstract: SummarySignal transduction pathways, which regulate cell growth and survival, are up-regulated in many cancers and there is considerable interest in their pharmaceutical modulation for cancer treatment. However inhibitors of single pathway components induce feedback mechanisms… read more here.
Keywords: pan mtor; treatment; pan akt; cancer cells ... See more keywords