Nicorandil protects podocytes via modulation of antioxidative capacity in acute puromycin aminonucleoside-induced nephrosis in rats
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Physiology - Renal Physiology"
DOI: 10.1152/ajprenal.00144.2022
Abstract: Nephrotic syndrome, characterized by proteinuria and hypoalbuminemia, results from the dysregulation of glomerular podocytes and is a significant cause of end-stage kidney disease. Patients with idiopathic nephrotic syndrome are generally treated with immunosuppressive agents; however,… read more here.
Keywords: pan rats; pan; puromycin aminonucleoside; physiology ... See more keywords
Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats
Sign Up to like & getrecommendations! Published in 2017 at "Physiological Reports"
DOI: 10.14814/phy2.13358
Abstract: Topiroxostat is a novel inhibitor of xanthine oxidase, and is postulated to exert a renoprotective effect. Puromycin aminonucleoside nephrosis (PAN) is a rat model of minimal change nephrotic syndrome. In this study, we examined whether… read more here.
Keywords: puromycin aminonucleoside; aminonucleoside nephrosis; pan rats; topiroxostat ... See more keywords