Profiling gene expression of antimony response genes in Leishmania (Viannia) panamensis and infected macrophages and its relationship with drug susceptibility.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.08.017
Abstract: The mechanisms of Leishmania resistance to antimonials have been primarily determined in experimentally derived Leishmania strains. However, their participation in the susceptibility phenotype in field isolates has not been conclusively established. Being an intracellular parasite,… read more here.
Keywords: susceptibility; gene expression; drug; panamensis ... See more keywords
Local Delivery of the Toll-Like Receptor 9 Ligand CpG Downregulates Host Immune and Inflammatory Responses, Ameliorating Established Leishmania (Viannia) panamensis Chronic Infection
Sign Up to like & getrecommendations! Published in 2017 at "Infection and Immunity"
DOI: 10.1128/iai.00981-16
Abstract: ABSTRACT Infection by Leishmania (Viannia) panamensis, the predominant etiologic agent for cutaneous leishmaniasis in Colombia, is characterized by a chronic mixed inflammatory response. Current treatment options are plagued by toxicity, lengthy treatment regimens, and growing… read more here.
Keywords: leishmania viannia; response; treatment; infection ... See more keywords
Ecological interactions of sand flies, hosts, and Leishmania panamensis in an endemic area of cutaneous leishmaniasis in Colombia
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011316
Abstract: Background The transmission dynamics of leishmaniasis are complex. There is also a lack of information about the ecological relationships between the vector/host/parasite at a more local and specific level. The Andean region concentrates more than… read more here.
Keywords: ecological interactions; panamensis; sand flies; cutaneous leishmaniasis ... See more keywords
Detection of Leishmania RNA Virus 1 in Leishmania (Viannia) panamensis Isolates, Panama
Sign Up to like & getrecommendations! Published in 2023 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2906.220012
Abstract: We detected Leishmania RNA virus 1 (LRV1) in 11 isolates of Leishmania (Viannia) panamensis collected during 2014–2019 from patients from different geographic areas in Panama. The distribution suggested a spread of LRV1 in L. (V.)… read more here.
Keywords: leishmania rna; viannia panamensis; panamensis; leishmania ... See more keywords
Insights into the Genetic Diversity of Leishmania (Viannia) panamensis in Panama, Inferred via Multilocus Sequence Typing (MLST)
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12050747
Abstract: Leishmaniasis is a disease caused by parasites of the genus Leishmania and transmitted by sand fly vectors. Tegumentary leishmaniasis is the most prevalent clinical outcome in Latin America, afflicting people from 18 countries. In Panama,… read more here.
Keywords: panamensis panama; panamensis; genetic diversity; insights genetic ... See more keywords