Panax notoginseng saponins ameliorate cisplatin‐induced mitochondrial injury via the HIF‐1α/mitochondria/ROS pathway
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12760
Abstract: Cisplatin is a major antineoplastic drug that is used to treat solid tumors, but its use is restricted by its nephrotoxicity. Such cisplatin‐induced nephrotoxicity (CIN) is believed to occur primarily through mitochondrial damage and reactive… read more here.
Keywords: hif; hif mitochondria; panax notoginseng; cisplatin ... See more keywords
Effects of panax notoginseng saponin on the pathological ultrastructure and serum IL‐6 and IL‐8 in pulmonary fibrosis in rabbits
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DOI: 10.1002/jcb.27045
Abstract: Panax notoginseng saponin (PNS) constitutes the major effective components of Panax notoginseng, which is widely used to treat microcirculatory disturbance associated diseases. In this study, we designed to investigate the effect of PNS on the… read more here.
Keywords: medicine; panax notoginseng; treatment; group ... See more keywords
Diversity and composition of rhizospheric soil and root endogenous bacteria in Panax notoginseng during continuous cropping practices
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201600464
Abstract: Rhizobacteria and endophytic bacteria play important roles in protecting host plants from infection by phytopathogens, which cause soil‐borne diseases and severely impair plant health. Panax notoginseng is negatively affected by continuous cropping and becomes vulnerable… read more here.
Keywords: cropping practices; panax notoginseng; diversity; root ... See more keywords
Quantitative comparison and rapid discrimination of Panax notoginseng powder and Caulis clematidis armandii using NMR combined with pattern recognition.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12264
Abstract: BACKGROUND The market demand for Panax notoginseng (P. notoginseng) is growing rapidly because of its useful properties in food and medicine. However, the frequent adulteration of P. notoginseng seriously affects the health of consumers and… read more here.
Keywords: recognition; caulis clematidis; panax notoginseng; clematidis armandii ... See more keywords
Comparative study on chemical components and anti-inflammatory effects of Panax notoginseng flower extracted by water and methanol.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700641
Abstract: Methanol and water are commonly used solvents for chemical analysis and traditional decoction, respectively. In the present study, a high-performance liquid chromatography with ultraviolet detection method was developed to quantify 11 saponins in Panax notoginseng… read more here.
Keywords: anti inflammatory; panax notoginseng; water; inflammatory effects ... See more keywords
Differentiating root and rhizome of panax notoginseng based on precursor ion scanning and multi heart-cutting two dimensional liquid chromatography.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200542
Abstract: Owing to an increasing demand for Panax notoginseng-based medicines and health products, establishing a fast, simple, and reliable assay to analyze the chemical differences between its root and rhizome is important. Although previous studies showed… read more here.
Keywords: liquid chromatography; panax notoginseng; root rhizome; notoginseng based ... See more keywords
Panax notoginseng saponins suppress lipopolysaccharide‐induced barrier disruption and monocyte adhesion on bEnd.3 cells via the opposite modulation of Nrf2 antioxidant and NF‐κB inflammatory pathways
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DOI: 10.1002/ptr.6488
Abstract: Dysfunction of the blood‐brain barrier (BBB) is a prerequisite for the pathogenesis of many cerebral diseases. Oxidative stress and inflammation are well‐known factors accounting for BBB injury. Panax notoginseng saponins (PNS), a clinical commonly used… read more here.
Keywords: notoginseng saponins; panax notoginseng; nrf2 antioxidant; adhesion bend ... See more keywords
Screening and evaluation of adventitious root lines of Panax notoginseng by morphology, gene expression, and metabolite profiles
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DOI: 10.1007/s00253-019-09778-z
Abstract: Panax notoginseng is a commonly used Traditional Chinese Medicine (TCM) and has diverse pharmacological activities with triterpenoid saponins as its main active ingredient. In the cultivation of P. notoginseng, continuous cropping is a serious problem,… read more here.
Keywords: panax notoginseng; root; gene expression; metabolite profiles ... See more keywords
A pathogenesis-related protein 10 gene PnPR10–3 was involved in molecular interaction between Panax notoginseng and Fusarium solani
Sign Up to like & getrecommendations! Published in 2019 at "Australasian Plant Pathology"
DOI: 10.1007/s13313-019-00644-0
Abstract: Pathogenesis-related proteins (PRs) are a great protein superfamily in plants and play important roles during plants respond to a variety of pathogens and environmental stress. In the present study, a PR10 gene, PnPR10–3, was isolated… read more here.
Keywords: tobacco; pathogenesis related; gene pnpr10; panax notoginseng ... See more keywords
Determination of arsenic speciation and the possible source of methylated arsenic in Panax Notoginseng.
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DOI: 10.1016/j.chemosphere.2016.10.093
Abstract: Arsenic species and a possible source of methylated arsenic in a Panax Notoginseng (PN) medicinal plant were explored to further understand the change of inorganic arsenic to the less toxic methylated form to minimize the… read more here.
Keywords: source methylated; arsenic panax; panax notoginseng; possible source ... See more keywords
Impacts of silicon addition on arsenic fractionation in soils and arsenic speciation in Panax notoginseng planted in soils contaminated with high levels of arsenic.
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DOI: 10.1016/j.ecoenv.2018.07.015
Abstract: Arsenic (As) is a well-known carcinogenic substance whose biological toxicity in soils and plants depends on its concentration and chemical forms. Silicon (Si) generally can alleviate biotic and abiotic stresses, including As stress. However, its… read more here.
Keywords: soil; speciation panax; addition; panax notoginseng ... See more keywords