Panbinostat decreases cFLIP and enhances killing of cancer cells by immunotoxin LMB-100 by stimulating the extrinsic apoptotic pathway
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DOI: 10.18632/oncotarget.20263
Abstract: LMB-100 (RG7787) is a recombinant immunotoxin, which kills mesothelin-expressing cancer cells and now being evaluated in phase 1 trials. To enhance the anti-tumor activity of LMB-100, we have searched for agents, already approved for cancer… read more here.
Keywords: decreases cflip; panbinostat decreases; lmb 100; pathway ... See more keywords