Targeting HSP90 sensitizes pancreas carcinoma to PD-1 blockade
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DOI: 10.1080/2162402x.2022.2068488
Abstract: ABSTRACT Interferon gamma (IFNG/IFNγ)-induced adaptive immune resistance remains a challenge for tumor therapy. We observed that the chaperone heat shock protein 90 (HSP90) stabilizes the transcription factor signal transducer and activator of transcription 1 (STAT1),… read more here.
Keywords: hsp90; pancreas carcinoma; targeting hsp90; hsp90 sensitizes ... See more keywords