GATA factors in pancreas development and disease
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2170
Abstract: There is an urgent need for the development of novel therapeutics options for diabetic patients given the high prevalence of diabetes worldwide and that, currently, there is no cure for this disease. The transplantation of… read more here.
Keywords: producing cells; pancreas development; disease; factors pancreas ... See more keywords
Animal Models of Pancreas Development, Developmental Disorders, and Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-2389-2_3
Abstract: The pancreas is a glandular organ responsible for diverse homeostatic functions, including hormone production from the endocrine islet cells to regulate blood sugar levels and enzyme secretion from the exocrine acinar cells to facilitate food… read more here.
Keywords: developmental disorders; pancreas development; development developmental; models pancreas ... See more keywords
Pancreas development and the Polycomb group protein complexes
Sign Up to like & getrecommendations! Published in 2020 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2020.103647
Abstract: The dual nature of pancreatic tissue permits both endocrine and exocrine functions. Enzymatic secretions by the exocrine pancreas help digestive processes while the pancreatic hormones regulate glucose homeostasis and energy metabolism. Pancreas organogenesis is defined… read more here.
Keywords: pancreas development; development; development polycomb; polycomb group ... See more keywords
Gotta Have GATA for Human Pancreas Development.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2017.04.004
Abstract: Haploinsufficient GATA6 mutations are associated with human pancreatic agenesis. Shi et al. (2017) in this issue of Cell Stem Cell and Tiyaboonchai et al. (2017) in a recent issue of Cell Reports utilize hPSCs to characterize GATA6… read more here.
Keywords: got gata; human pancreas; pancreas development; gata human ... See more keywords
Mitochondrial Protein UCP2 Controls Pancreas Development
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes"
DOI: 10.2337/db17-0118
Abstract: The mitochondrial carrier uncoupling protein (UCP) 2 belongs to the family of the UCPs. Despite its name, it is now accepted that UCP2 is rather a metabolite transporter than a UCP. UCP2 can regulate oxidative… read more here.
Keywords: controls pancreas; mitochondrial protein; pancreas development; ucp2 controls ... See more keywords
Mig6 Is Required for Pancreas Development in Zebrafish
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.2337/db18-2122-p
Abstract: Strategies to promote β cell neogenesis could be used to restore functional β cell mass in both type 1 and type 2 diabetes. Here we examine the role of mitogen-inducible gene 6 ( mig6, a.k.a.… read more here.
Keywords: mig6 required; pancreas development; role; mig6 ... See more keywords
Integrative analysis of the inverse expression patterns in pancreas development and cancer progression
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i32.4727
Abstract: BACKGROUND As the malignant tumor, pancreatic cancer with a meager 5-years survival rate has been widely concerning. However, the molecular mechanisms that result in malignant transformation of pancreatic cells remain elusive. AIM To investigate the… read more here.
Keywords: pancreas development; pancreatic cancer; development cancer; expression ... See more keywords