Survival After Minimally Invasive vs Open Surgery for Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.48147
Abstract: Key Points Question Is minimally invasive pancreatic surgery (MIPS) associated with better long-term survival compared with open pancreatic surgery (OPS) among patients with pancreatic adenocarcinoma? Findings In this study of 396 patients, the median overall… read more here.
Keywords: surgery; invasive open; pancreatic adenocarcinoma; survival minimally ... See more keywords
Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.3420
Abstract: Importance Although patients with resected pancreatic adenocarcinoma are at high risk for disease recurrence, few biomarkers are available to inform patient outcomes. Objective To evaluate the alterations of the 4 main driver genes in pancreatic… read more here.
Keywords: patients resected; driver genes; resected pancreatic; pancreatic adenocarcinoma ... See more keywords
Screening of an annexin‐A2‐targeted heptapeptide for pancreatic adenocarcinoma localization
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13352
Abstract: Annexin A2 (ANXA2) encodes an oncoprotein whose expression has been found to correlate with poorer overall survival (OS) of pancreatic adenocarcinoma (PAAD) patients. Although peptides are available for targeting ANXA2, none of these were initially… read more here.
Keywords: pancreatic adenocarcinoma; cy7; screening annexin; cy7 yw7 ... See more keywords
Preoperative therapy for pancreatic adenocarcinoma—precision beyond anatomy
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DOI: 10.1002/cncr.34273
Abstract: Despite recent advances in the systemic treatment of gastrointestinal tumors, pancreatic adenocarcinoma (PDAC) remains a challenging disease, with 5‐year survival just over 10%. Pancreatectomy in patients meeting defined anatomic criteria can result in cure; however,… read more here.
Keywords: precision; pancreatic adenocarcinoma; anatomy; preoperative therapy ... See more keywords
Circulating tumor‐associated autoantibodies as novel diagnostic biomarkers in pancreatic adenocarcinoma
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DOI: 10.1002/ijc.34334
Abstract: To develop a superior diagnostic approach for pancreatic adenocarcinoma (PAAC), the present study prospectively included 338 PAAC patients, 294 normal healthy volunteers (NHV), 122 chronic pancreatitis (CP) patients and 100 patients with non‐PAAC malignancies. In… read more here.
Keywords: cldn17; paac; pancreatic adenocarcinoma; associated autoantibodies ... See more keywords
Can diffusion‐weighted imaging serve as a biomarker of fibrosis in pancreatic adenocarcinoma?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25581
Abstract: To assess the relationship between diffusion‐weighted imaging (DWI) and intravoxel incoherent motion (IVIM)‐derived quantitative parameters (apparent diffusion coefficient [ADC], perfusion fraction [f], Dslow, diffusion coefficient [D], and Dfast, pseudodiffusion coefficient [D*]) and histopathology in pancreatic… read more here.
Keywords: imaging serve; diffusion; pancreatic adenocarcinoma; weighted imaging ... See more keywords
Patterns of disease relapse and posttreatment follow‐up of patients with resected pancreatic adenocarcinoma: A single‐center analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26985
Abstract: To describe the patterns of disease relapse and follow‐up of patients with resected pancreatic adenocarcinoma. Additionally, we looked at patients' characteristics at relapse and survival. read more here.
Keywords: follow patients; resected pancreatic; pancreatic adenocarcinoma; disease relapse ... See more keywords
Gastroenterology and pancreatic adenocarcinoma: what the radiologist needs to know
Sign Up to like & getrecommendations! Published in 2017 at "Abdominal Radiology"
DOI: 10.1007/s00261-017-1347-5
Abstract: In this article, we review the information that radiologists need to know regarding the endoscopic approach to the diagnosis and management of pancreatic cancer. This includes a review of the indications, techniques, and complications of… read more here.
Keywords: needs know; gastroenterology; pancreatic adenocarcinoma; adenocarcinoma radiologist ... See more keywords
Prognostic Scoring System for Patients Who Present with a Gastric Outlet Obstruction Caused by Advanced Pancreatic Adenocarcinoma
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DOI: 10.1007/s00268-017-4027-2
Abstract: BackgroundGastroenterostomy and stent placement are the most common palliative procedures for patients with a gastric outlet obstruction caused by advanced pancreatic adenocarcinoma. Gastroenterostomy is regarded as the optimum treatment for patients in whom a longer… read more here.
Keywords: caused advanced; advanced pancreatic; pancreatic adenocarcinoma; obstruction caused ... See more keywords
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
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DOI: 10.1007/s11010-020-03751-5
Abstract: Tumor cells increase glucose metabolism through glycolysis and pentose phosphate pathways to meet the bioenergetic and biosynthetic demands of rapid cell proliferation. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) are key regulators of glucose metabolism via their… read more here.
Keywords: glycolysis; pancreatic adenocarcinoma; proliferation; proliferation pancreatic ... See more keywords
Genetic landscape of pancreatic adenocarcinoma patients: a pilot study from Pakistan.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06964-z
Abstract: BACKGROUND Pancreatic adenocarcinoma is one of the most aggressive malignancies with extremely low survival rate. Studies have shown that the exploration of key genes can provide a basis for targeted treatment of these patients. The… read more here.
Keywords: pilot study; pancreatic adenocarcinoma; adenocarcinoma patients; adenocarcinoma ... See more keywords