Precision medicine for pancreatic diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in gastroenterology"
DOI: 10.1097/mog.0000000000000665
Abstract: PURPOSE OF REVIEW We describe and contrast the strengths of precision medicine with Western medicine, and complex trait genetics with Mendelian genetics. Classic genetics focuses on highly penetrant pathogenic variants in a single gene believed… read more here.
Keywords: medicine; pancreatic diseases; medicine pancreatic; precision medicine ... See more keywords
Pancreas Academy: A Conference-Based Approach for Improving Education in Pancreatic Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Pancreas"
DOI: 10.1097/mpa.0000000000001820
Abstract: ABSTRACT The Collaborative Alliance for Pancreatic Education and Research developed Pancreas Academy as a lecture-based conference with the goal of providing practical guidance in the diagnosis and management of pancreatic diseases for health care providers.… read more here.
Keywords: diseases pancreas; pancreatic diseases; education; pancreas academy ... See more keywords
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases
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DOI: 10.1097/mpa.0000000000002170
Abstract: Abstract The “Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases” Workshop was a 1.5-day scientific conference at the National Institutes of Health (Bethesda, MD) that engaged clinical and basic science investigators interested… read more here.
Keywords: physiology exocrine; exocrine endocrine; physiology; endocrine compartments ... See more keywords
Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells International"
DOI: 10.1155/2019/9301382
Abstract: Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are characterized by their unique capacity to stepwise differentiate towards any particular cell type in an adult organism. Pluripotent stem cells provide a beneficial platform… read more here.
Keywords: stem cells; model; pluripotent stem; cancer ... See more keywords
Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties
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DOI: 10.1158/0008-5472.can-19-3534
Abstract: Primary fibroblasts derived from various types of pancreatic diseases possess and retain distinct molecular and functional characteristics in culture, providing a series of cellular models for treatment development and disease-specific research. Although fibrotic stroma forms… read more here.
Keywords: associated fibroblasts; pancreatic diseases; disease specific; research ... See more keywords
PAR2: The cornerstone of pancreatic diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological research"
DOI: 10.33549/physiolres.934931
Abstract: It has been 30 years since the first member of the protease-activated receptor (PAR) family was discovered. This was followed by the discovery of three other receptors, including PAR2. PAR2 is a G protein-coupled receptor… read more here.
Keywords: pancreatic diseases; receptor; cornerstone pancreatic; par2 cornerstone ... See more keywords
Gut Dysbiosis in Pancreatic Diseases: A Causative Factor and a Novel Therapeutic Target
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.814269
Abstract: Pancreatic-related disorders such as pancreatitis, pancreatic cancer, and type 1 diabetes mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even though our understanding of the initiation and progression of pancreatic diseases has… read more here.
Keywords: dysbiosis pancreatic; gut dysbiosis; causative factor; diseases causative ... See more keywords
Pancreas—Its Functions, Disorders, and Physiological Impact on the Mammals’ Organism
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.807632
Abstract: This review aimed to analyze the scientific literature on pancreatic diseases (especially exocrine pancreatic insufficiency). This review also describes the correlation between the physiological fitness of the pancreas and obesity. The influence of the pancreatic… read more here.
Keywords: functions disorders; pancreatic diseases; pancreas functions; physiological impact ... See more keywords
Understanding Necroptosis in Pancreatic Diseases
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DOI: 10.3390/biom12060828
Abstract: Intermediate between apoptosis and necrosis, necroptosis is a regulated caspase-independent programmed cell death that induces an inflammatory response and mediates cancer development. As our understanding improves, its role in the physiopathology of numerous diseases, including… read more here.
Keywords: necroptosis; understanding necroptosis; necroptosis pancreatic; pancreatic diseases ... See more keywords
Innate Lymphoid Cells: Emerging Players in Pancreatic Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073748
Abstract: Common pancreatic diseases have caused significant economic and social burdens worldwide. The interstitial microenvironment is involved in and plays a crucial part in the occurrence and progression of pancreatic diseases. Innate lymphoid cells (ILCs), an… read more here.
Keywords: innate lymphoid; pancreatic diseases; pancreatic disease; players pancreatic ... See more keywords
Nutritional Support in Pancreatic Diseases
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DOI: 10.3390/nu14214570
Abstract: This review summarizes the main pancreatic diseases from a nutritional approach. Nutrition is a cornerstone of pancreatic disease and is sometimes undervalued. An early identification of malnutrition is the first step in maintaining an adequate… read more here.
Keywords: support pancreatic; diseases nutritional; nutrition; pathology ... See more keywords